APAC Aminoglycosides Market Analysis

The APAC Aminoglycosides Market stood at around xx Bn in 2023 and is projected to reach US $xx Bn by 2033, exhibiting a CAGR of xx% during the forecast period.

The APAC Aminoglycosides Market Analysis Executive Summary

Aminoglycosides are antibacterial agents that act against aerobic Gram-negative microorganisms in this group of antibiotics, the predominant mechanism of action involves binding to the 30S ribosomal subunit in order to inhibit protein synthesis in bacterial cells and hence, killing them. Some examples of aminoglycosides are streptomycin, gentamycin, tobramycin, and amikacin. These drugs are commonly injected because of their poor oral bioavailability and their use is restricted to severe infections due to side effects that include nephrotoxicity and ototoxicity. Nonetheless, aminoglycosides present certain risks and are even more important for treating multidrug-resistant bacteria and are often combined with other antibiotics to improve efficacy or counteract resistance mechanisms. In the U.S., more than 2.8 million antimicrobial-resistant infections occur each year. More than 35,000 people die as a result, according to CDC's 2019.

The drivers for the aminoglycosides market are increasing bacterial infections and the rising trend of antibiotic resistance Global support for health and awareness crusade enhances growth. However, it has some risks like high side effect profiles, lengthy approval procedures, and a fiercely competitive environment for the pharmaceutical industries. It is difficult to treat them due to poor oral bioavailability that restricts them to injectable preparations. The regulatory framework for clinical research and development is robust, while the insurance and cost analyses of effectiveness are mixed. In a word, it is a large market but not without challenges.    

APAC Aminoglycosides Market Dynamics

Market Growth Drivers

The higher frequency of bacterial infections, which leads to the need for effective antibiotics, the high incidence of respiratory diseases in which aminoglycosides play a vital role, the necessity to improve the diagnosis and treatment of many diseases; the increase in the number of patients, especially in the Asia-Pacific region, mainly due to the better development of the healthcare sector, continuing research activities to improve existing and develop new products containing aminoglycosides Besides, increased incidence of animal diseases and an increasing elderly population also boost the market.

Opportunity

The promising avenues that are expected to transform the prospects of aminoglycoside market in future are the growth in emerging economies like Asia-Pacific and Africa, partnerships between different pharma companies and research institutes for the discovery of new aminoglycosides, emerging focus on personalized drugs, increase in R and D by companies for introducing new forms, combination therapies, increasing focus on outpatient treatment, increasing use of generics and the use of smart technologies.

Market Restraints

Aminoglycosides have several drawbacks regarding their application and market expansion. Severe adverse effects including nephrotoxicity and ototoxicity place constraints on their use especially in certain demographics. The discover of new antibiotic-resistant bacteria neutralizes the use and therefore shifts focus to other modes of treatment. New formulation approval processes take a long duration to obtain thus preventing the market entry, competition among the pharmaceutical companies is high and this leads to price undercutting and decreased profitability margins. Their poor oral bioavailability limits the practical use of products to injections and thus reduces patient compliance. Further, economic volatility impacts the cost and availability, especially in a country with a constrained healthcare budget. Both these angles contribute towards the overall geography and restraint of the aminoglycosides market.

Competitive Landscape Aminoglycosides Market in APAC

Key Players

• Pfizer Inc. 
• AbbVie Inc. (Allergan Plc)
• Teva Pharmaceutical Industries Ltd
• Zoetis Inc
• Kremoint Pharma Pvt. Ltd.
• Cipla Limited
• HuvePharma 

Recent Developments

February 2024, Cipla gets approval to introduce antibiotic injection to treat UTIs in India, holds the patent for plazomicin sulfate, an intravenous aminoglycoside administered once daily.

Merger and Acquisition

In November 2023, Pfizer made a major move in the pharmaceutical industry by acquiring Nektar Therapeutics for $7.5 billion. This strategic acquisition strengthens Pfizer's antibiotic portfolio, with a specific emphasis on the aminoglycosides sector.

Healthcare Policies and Regulatory Landscape for Aminoglycosides Market in APAC

Policy changes and Reimbursement scenario

Policies promoting antibiotic stewardship and funding for research support the development of new formulations and improve market growth potential. Public health campaigns raise awareness about antibiotic resistance, driving demand for effective treatments. However, reimbursement for aminoglycosides varies by region and insurance provider, which can affect patient access. Cost-effectiveness evaluations and patient assistance programs are becoming more important as healthcare systems shift towards value-based care. Additionally, increased focus on antibiotic stewardship programs influences reimbursement policies, ensuring that effective treatments remain available. These factors collectively shape the accessibility and market dynamics of aminoglycosides.